Rapid Fabrication of Membrane-Integrated Thermoplastic Elastomer Microfluidic Devices
نویسندگان
چکیده
منابع مشابه
High-throughput Fabrication of Advanced 3d Microfluidic Devices in Thermoplastic Elastomer for Biological Probe Immobilization
We have developed a process based on hot-embossing lithography (HEL) to pattern at high-throughput micron-size through-holes in thin thermoplastic elastomer (TPE) membranes. This novel HEL process, which is shown to provide key advantages for microfluidics applications, was applied to the fabrication of highly-integrated 3D microfluidic devices designed to precisely immobilize biomolecules on t...
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Polydimethylsiloxane (PDMS) has numerous desirable properties for fabricating microfluidic devices, including optical transparency, flexibility, biocompatibility, and fabrication by casting; however, partitioning of small hydrophobic molecules into the bulk of PDMS hinders industrial acceptance of PDMS microfluidic devices for chemical processing and drug development applications. Here we descr...
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A method for integrating on-chip displacement micropumps in thermoplastic microfluidic devices is presented. Stainless steel screws serve as direct displacement pumping elements integrated directly into threaded ports formed in a thermoplastic substrate, with a microcontroller used to precisely modulate flow rates over a wide range from 0.5 – 35 μL/min, in a compact and portable format. Combine...
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A very simple and fast method for the fabrication of poly(dimethylsiloxane) (PDMS) microfluidic devices is introduced. By using a photocopying machine to make a master on transparency instead of using lithographic equipment and photoresist, the fabrication process is greatly simplified and speeded up, requiring less than 1.5 h from design to device. Through SEM characterization, any micro-chann...
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ژورنال
عنوان ژورنال: Micromachines
سال: 2020
ISSN: 2072-666X
DOI: 10.3390/mi11080731